My research centres on making neuroimaging more rigorous and reproducible. This spans three overlapping areas: community standards for data organisation and sharing, statistical methods for M/EEG and fMRI, and the tools and infrastructure that make open science tractable at scale. Only with rigorous and reproducible results can we have good clinical applications.
Research Themes
Methods for Neuroimaging
Standard parametric methods applied mass-univariately at the sensor or voxel level carry assumptions that are routinely violated in neuroimaging data — non-normality, outliers, mis-specified models, and inflated false positives from multiple comparisons. I develop and maintain tools for robust estimation (trimmed means, robust correlations, Winsorised statistics), hierarchical GLM for EEG/MEG (LIMO MEEG), adaptive thresholding for single-subject fMRI maps, and methods for single-trial ERP analysis.
Related: LIMO MEEG · SPMup · Robust Statistical Toolbox
Scientific Data Management
Much of the field’s reproducibility problem is upstream of analysis — in how data are collected, described, and shared. I co-lead or contribute to several community efforts that define how this should work: BIDS extensions for EEG, Genetics, and PET; the OHBM COBIDAS guidelines for M/EEG and MRI; and the Open Brain Consent templates that allow participants to authorise open sharing under GDPR. The common thread is building community consensus around practices that make individual studies reusable. I am also intereted in privacy issues, how to measure and quantify risks.
Related:
COBIDAS MEEG ·
BIDS ·
Open Brain Consent ·
Join us on the BIDS EEG Derivatives (BEP021) Standard
MetaPrivBIDS
Brain Structures & Functions with clinical applications
I have broad interest in cognition, in particular categorization processes (language, voices, faces, objects, ..), and altered cognitive performance in diseases (dyslexia, epilepsy, brain tumors, psychiatric disorders). I am particularly interested in methods allowing to detect or predict conditions and reponses to treatments.